Asia/Pacific
Australia
Europe
Africa
North
America
South
America
United States
Status: Issued
Patent #: 5,753,506 and 6,040,180
Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals (div)
United States
Status: Issued
Patent #: 6,284,539
Method for generating dopaminergic cells derived from neural precursors
United States
Status: Issued
Patent #: 7,544,511
Stable neural stem cell lines (div)
United States
Status: Issued
Patent #: 7,560,553 and 7,858,628
Use of fused nicotinamides to promote neurogenesis (div)
Ann Arbor, Michigan: FDA-approved NSI-566/Phase II trial for ALS expected to commence in second half of 2013. Phase II expands to two centers: ALS Clinic at University of Michigan Health System joins Emory University Hospital, site of Phase I.
More
United States
Status: Issued
Patent #: 7,691,629
Methods of treating spinal cord injury (div)
United States
Status: Pending
Application #: 12/404,841, and 12/710,097
Methods of treating spinal cord injury (div)
United States
Status: Pending
Application #: 11/852,922
Method for discovering neurogenic agents
United States
Status: Pending
Application #: 61/368,409
Methods for treating and/or reversing neurodegenerative diseases and/or disorders
United States
Status: Exclusive Worldwide License to Patent #: 8,092,495
Spinal Platform and Method for Delivering a Therapeutic Agent to a Spinal Cord Target
United States
Status: Pending
Application #: 12/424,238
Stable neural stem cell lines (div)
United States
Status: Issued
Patent #: 8,030,492
Compositions to effect neuronal growth
United States
Status: Exclusive Worldwide License to Issued & Pending Patents
Patent #: 7,833,217
Application #: 12/913,527
Floating Spinal Cannula and Method of Use
United States
Status: Issued
Patent #: 8,058,434
Compositions to effect neuronal growth
United States
Status: Issued
Patent #: 8,236,299
Transplantation of human neural cells for treatment of neurodegenerative conditions
Canada
Status: Pending
Application #: 2343571
Stable neural stem cell lines
Canada
Status: Pending
Application #: 2257068
Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
United Kingdom
Status: Issued
Patent #: 0915968
Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
Switzerland
Status: Issued
Patent #: 0915968
Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
Sweden
Status: Issued
Patent #: 0915968
Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
Spain
Status: Issued
Patent #: 0915968
Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
Ireland
Status: Issued
Patent #: 0915968
Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
Germany
Status: Issued
Patent #: 69737949.3
Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
France
Status: Issued
Patent #: 0915968
Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
Norway
Status: Pending
Application #: 20073078
Methods of treating spinal cord injury
Federation of Russia
Status: Pending
Application #: 2007122507
Methods of treating spinal cord injury
European Patent Organisation (EPO)
Status: Pending
Application #: 99948396.9
Stable neural stem cell lines
European Patent Organisation (EPO)
Status: Pending
Application #: 037903564
Method for discovering neurogenic agents
European Patent Organisation (EPO)
Status: Pending
Application #: 05851748.3
Methods of treating spinal cord injury
Australia
Status: Issued
Patent #: 755849
Stable neural stem cell lines
Singapore
Status: Issued
Patent #: 132324
Methods of treating spinal cord injury
Japan
Status: Issued
Patent #: 4709382
Stable neural stem cell lines (div)
Japan
Status: Pending
Application #: 2007-543219
Methods of treating spinal cord injury
Japan
Status: Pending
Application #: 2010-254952
Stable neural stem cell lines (div)
Vietnam
Status: Pending
Application #: 1-2007-01216
Methods of treating spinal cord injury
South Korea
Status: Pending
Application #: 10-2007-7012097
Methods of treating spinal cord injury
Philippines
Status: Pending
Application #: 1-2007-501016 and 1-2010-502167
Methods of treating spinal cord injury (div)
India
Status: Pending
Application #: 2613/CHENP/2007
Methods of treating spinal cord injury
China
Status: Pending
Application #: 200580039450
Methods of treating spinal cord injury
Hong Kong
Status: Pending
Application #: 8106303.1
Methods of treating spinal cord injury
Israel
Status: Pending
Application #: 183092
Methods of treating spinal cord injury (div)
Israel
Status: Pending
Application #: 204356
Methods of treating spinal cord injury (div)
United Arab Emirates
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Antigua and Barbuda
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Albania
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Armenia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Angola
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Austria
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Australia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Azerbaijan
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Bosnia and Herzegovina
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Barbados
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Belgium
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Burkina Faso
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Bulgaria
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Bahrain
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Benin
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Brazil
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Botswana
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Belarus
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Belize
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Canada
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Central African Republic
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Congo
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Switzerland
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Côte d'Ivoire
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Chile
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Cameroon
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
China
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Colombia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Costa Rica
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Cuba
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Cyprus
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Czech Republic
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Germany
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Denmark
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Dominica
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Dominican Republic
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Algeria
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Ecuador
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Estonia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Egypt
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Spain
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Finland
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
France
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Gabon
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
United Kingdom
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Grenada
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Georgia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Ghana
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Gambia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Guinea
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Equatorial Guinea
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Greece
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Guatemala
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Guinea-Bissau
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Honduras
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Croatia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Hungary
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Indonesia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Ireland
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Israel
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
India
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Iceland
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Italy
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Japan
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Kenya
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Kyrgyzstan
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Comoros
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Saint Kitts and Nevis
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Korea, Democratic People's Republic of
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Korea, Republic of
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Kazakhstan
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Lao People's Democratic Republic
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Saint Lucia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Liechtenstein
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Sri Lanka
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Liberia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Lesotho
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Lithuania
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Luxembourg
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Latvia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Libyan Arab Jamahiriya
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Morocco
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Monaco
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Moldova, Republic of
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Montenegro
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Madagascar
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Macedonia, the former Yugoslav Republic of
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Mali
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Mongolia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Mauritania
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Malta
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Malawi
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Mexico
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Mexico City: ALS Phase I / II Trial expected to commence in the second half of 2013, using NSI-566 spinal cord stem cells.
More
Malaysia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Mozambique
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Namibia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Niger
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Nigeria
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Nicaragua
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Netherlands
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Norway
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
New Zealand
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Oman
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Peru
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Papua New Guinea
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Philippines
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Poland
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Portugal
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Romania
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Serbia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Russian Federation
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Russian Federation
Status: Issued
Stem cell transplantation to treat neurodegenerative conditions
Seychelles
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Sudan
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Sweden
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Singapore
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Slovenia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Slovakia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Sierra Leone
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
San Marino
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Senegal
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Sao Tome and Principe
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
El Salvador
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Syrian Arab Republic
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Swaziland
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Chad
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Togo
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Thailand
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Tajikistan
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Turkmenistan
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Tunisia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Turkey
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Trinidad and Tobago
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Tanzania, United Republic of
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Ukraine
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Uganda
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
United States
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Uzbekistan
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Saint Vincent and the Grenadines
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Vietnam
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
South Africa
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Zambia
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Zimbabwe
Status: Pending
Application #: PCT/US2010/046537
Synthesis of a neurostimulative piperazine
Atlanta: FDA-approved NSI-566/Phase II trial for ALS expected to commence in second half of 2013. Phase II expands to two centers: Emory University Hospital, site of Phase I, and ALS Clinic at University of Michigan Health System.
More
Pasadena: Ongoing Phase I trial for neurogenic small molecule drug, NSI-189, to treat major depressive disorder. Trial advanced to third and final cohort of Phase Ib, testing escalating doses for 28 daily administrations, in April 2013 and is expected to conclude in 3Q13.
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Loma Linda: U.S. Department of Defense-funded pre-clinical research program, entitled “Research to Treat Cancerous Brain Tumors with Neural Stem Cells,” in collaboration with Loma Linda University.
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Suzhou: Neuralstem China 神脑生物医药公司 (Suzhou Neuralstem Biopharmaceutical Company, Ltd.), a wholly owned subsidiary, launched in June 2010 with the intention of conducting stem cell clinical trials in the People’s Republic of China.
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Beijing: Collaborating with
BaYi Brain Hospital in Beijing to conduct a Phase I/II trial to treat ischemic stroke using NSI-566 spinal cord stem cells. Trial expected to commence in 2Q13.
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South Korea: Neuralstem has an exclusive option agreement with CJ Cheil Jedang Corporation, for cell therapy products in South Korea, Indonesia, Malaysia, Philippines, Singapore and Vietnam.
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South Korea: Acute SCI Phase I Trial expected to commence in the second half of 2013, in collaboration with partner CJ CheilJedang.
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Indonesia: Neuralstem has an exclusive option agreement with CJ Cheil Jedang Corporation, for cell therapy products in South Korea, Indonesia, Malaysia, Philippines, Singapore and Vietnam.
More
Malaysia: Neuralstem has an exclusive option agreement with CJ Cheil Jedang Corporation, for cell therapy products in South Korea, Indonesia, Malaysia, Philippines, Singapore and Vietnam.
More
Philippines: Neuralstem has an exclusive option agreement with CJ Cheil Jedang Corporation, for cell therapy products in South Korea, Indonesia, Malaysia, Philippines, Singapore and Vietnam.
More
Singapore: Neuralstem has an exclusive option agreement with CJ Cheil Jedang Corporation, for cell therapy products in South Korea, Indonesia, Malaysia, Philippines, Singapore and Vietnam.
More
Vietnam: Neuralstem has an exclusive option agreement with CJ Cheil Jedang Corporation, for cell therapy products in South Korea, Indonesia, Malaysia, Philippines, Singapore and Vietnam.
More