Neuralstem in the News


  • With three first-in-human trials, therapeutic stem cell science takes a bold step

By Science Daily, October 21, 2014

University of California, San Diego Health Sciences reports on the first of four patients, who was treated in late September 2014, in the commencement of Neuralstem’s Phase I NSI-566/chronic spinal cord injury (cSCI) trial. The Science Daily story reviews this first FDA-approved trial for cSCI as one of three ground-breaking stem cell efforts underway at UCSD, supported by the Sanford Stem Cell Clinical Center.

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  • “After the Ice Bucket” - Neuralstem NSI-566/ALS Interview with Richard Garr

By Steve Usdin, Host, “BioCentury This Week,” October 19, 2014

Neuralstem's President and CEO, Richard Garr, sets out the company’s progress towards its goal of creating a neural stem cell therapy that will make ALS a manageable chronic disease and give patients a normal lifespan and good quality of life in this nearly six-minute TV segment, one of four on the future of ALS research produced by BioCentury in partnership with WUSA9, the CBS affiliate in Washington, D.C. Mr. Garr gives a thorough overview of NSI-566/ALS, including the neural stem cells; specially designed surgical devices used for the world’s first intraspinal injections; “rescue, nurture and integrate” treatment benefits, and Phase I final cohort three-year results from peer-reviewed, published data. NSI-566/ALS Phase II trials concluded final surgeries in July 2014.

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  • Spinal gap: Neuralstem goes into chronic injuries phase I, first ever cleared by FDA

By Randy Osborne, BioWorld Today, October 10, 2014

Neuralstem’s President and CEO, Richard Garr, is interviewed in this cover story reporting on the promise of Neuralstem’s NSI-566/chronic spinal cord injury (cSCI) Phase I trial, now underway at the University of California, San Diego School of Medicine. This trial, like Neuralstem’s ongoing NSI-566/ALS trials, represents the first FDA-approved stem cell trial for the indication. While both trials use the same cells and similar procedure, Mr. Garr explains that in addition to neurotrophic factors, in spinal cord injury patients the NSI-566 mechanism of action includes rebuilding neural circuitry for structural repair, “literally bridging the gap… trying to rebuild the circuitry in the gap so that the signal can come through, down the spinal cord.”

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  • Opinion: This tiny biotech company takes the real ice bucket challenge

By Michael Brush, MarketWatch, September 2, 2014

Financial writer, Michael Brush, looks ahead of the $100 million-plus raised in the ALSA Ice Bucket Challenge to the potential of biotech treatments for ALS. Neuralstem’s recently completed NSI-566/ALS Phase II and upcoming Phase II/III trials are the focus of the opinion piece. Principal Investigator, Eva Feldman, MD, PhD, notes that she hopes “the ice bucket money goes to fast-tracking new therapies,” and Neuralstem’s President and CEO, Richard Garr, projects that, “We could be as close as two years away from commercialization.”

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  • Research making ALS less of a mystery

By Jonathan LaPook, MD, CBS Evening News with Scott Pelley, September 1, 2014

CBS’s chief medical correspondent features Neuralstem NSI-566/ALS patient and trial on CBS national news story as a promising ALS treatment.

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Crain’s Detroit Business explores NSI-566 next steps with ALS P.I., Dr. Eva Feldman, and reviews additional indication, Alzheimer’s disease, following promising animal research. | 8.1.14
The Wall Street Journal interviews President/CEO, Richard Garr, on patient-directed social media’s impact on trials. NSI-566/ALS patients have independently chosen to blog online. | 7.30.14
FORBES' feature quotes President/CEO Richard Garr extensively, on the differentiation and commercialization of Neuralstem’s proprietary cell technology. | November 2013
FOX Medical Team's Beth Galvin continues her NSI-566/ALS coverage at Emory with a patient’s perspective segment. Phase I patients, Ted Harada and John Conley, are featured. | 11.20.13
Bethesda Magazine feature provides rich insights on Neuralstem’s “potential wonder drug aimed specifically at rebuilding the hippocampus”: NSI-189. | November-December 2013
Practical Neurology interviews Chairman and CSO Dr. Karl Johe and P.I. Dr. Eva Feldman about the NSI-566/ALS trials in “Decreasing Progression, Increasing Function.” | October 2013
FOX News Detroit walks with NSI-566/ALS Phase I patient Ted Harada and P.I. Dr. Eva Feldman on the eve of the Phase II trial. | 8.28.13
Bioscience Technology ALS P.I. Dr. Eva Feldman and Neuralstem’s President/CEO Richard Garr in a feature that explores data from six extraordinary ALS responders – “as rare as a red wolf.” | 5.30.13
MIT's Technology Review reports on CELL SCI research showing “paralyzed rats walk again after stem cell transplant” of NSI-566, suggesting hope for treatment of spinal cord injury. | 9.13.12